Spec Sheet

Stemolecule™ Epigenetic Modifier Set

Catalog #	Size	Price (USD)	Quantity
00-0039	4 compounds	$259.00	Qty:

The Stemolecule™ Epigenetic Modifier Set is a complete set of small molecules for modulating epigenetic effects of DNA and histones. The set consists of four cell-permeable small molecules: BIX01294, Sodium Butryate, RG108, and Valproic Acid (VPA). BIX01294 is a selective inhibitor of G9a HMTase, Sodium Butryate is an inhibitor of histone deacetylases, RG108 is a DNA methyltransferase inhibitor, and VPA is an inhibitor of histone deacetylases. Each small molecule is tested for purity, accurate mass and structure, and toxicity in mouse embryonic stem cells.

Image
Video

Stemolecules™ BIX1294, Valproic Acid, Sodium Butyrate, and RG108 modulate epigenetic effects of DNA and histones.

General
Specs
Technical Documents

Stemolecule™ Epigenetic Modifier Set

The Stemolecule™ Epigenetic Modifier Set contains four cell permeable small molecules known to modulate DNA or histone modifications. Stemolecule™ BIX01294 is a selective inhibitor of G9a histone methyl transferase (G9a HMTase). Stemolecule™ RG108 is a DNA methyltransferase inhibitor. Stemolecule™ Sodium Butyrate is an inhibitor of histone deacetylases. Stemolecule™ Valproic Acid (VPA) is an inhibitor of histone deacetylases.

Related Products
Stemolecule™ MAPK Signaling Pathway Modulator Set (Cat. No. 00-0041)
Stemolecule™ TGF-beta Signaling Pathway Modulator Set (Cat. No. 00-0038)
Stemolecule™ iPS Cell Enhancer Set (Cat. No. 00-0040)
Stemolecule™ ROCK Signaling and Survival Pathway Set (Cat. No. 00-0057)
Stemolecule™ Wnt Signaling Pathway Set (Cat. No. 00-0059)
Stemolecule™ SHH Signaling Pathway Modulator Set (Cat. No. 00-0058)

For research use only. Not for use in diagnostic procedures. Not for resale.

Stemolecule™ Epigenetic Modifier Set

Size	4 compounds
Lot Number	1258
Quantity / Size	4 compounds
Set Components	1. Stemolecule™ BIX01294 (Cat. No. 04-0002), 5 mg, Lot# 1199 2. Stemolecule™ RG108 (Cat. No. 04-0001), 10 mg, Lot# 1198 3. Stemolecule™ Sodium Butyrate (Cat. No. 04-0005), 500 mg, Lot# 1001 4. Stemolecule™ Valproic Acid (Cat. No. 04-0007), 5 g, Lot# 1090
Storage	Store at 4°C. Protect from light. Following reconstitution, store aliquots at -20°C.
Stability	Components are stable for 6 months from date of receipt when stored as directed.
Quality control	The purity of Stemgent’s Stemolecules™ was determined by HPLC analysis. The accurate mass and structure of Stemgent’s Stemolecules™ were determined by mass spectrometry and NMR, respectively. Cellular toxicity of Stemgent’s Stemolecules™ was tested on mouse embryonic stem cells.
Recommended Usage	Refer to individual Stemolecule™ specification sheets.
Related Products	Stemolecule™ TGF-β Signaling Pathway Modulator Set (Cat.No.00-0038) Stemolecule™ MAPK Signaling Pathway Modulator Set (Cat.No.00-0041) Stemolecule™ iPS Cell Enhancers Set (Cat.No.00-0040)
Notice to Purchaser	Purchaser represents and warrants that it will use the Stemolecule™ Epigenetic Modifier Set purely for research purposes. Not for diagnostic use, not for resale, and not for use in humans or veterinary applications. Stemgent will not be held responsible for patent infringement or other violations that may occur with the use of our products.