Products & Services
Stemgent offers advanced stem cell-qualified reagents and
tools developed by some of the world's leading stem cell scientists.
Stemolecule™ MAPK Signaling Pathway Modulator Set
|
|
|
|
Product Overview
The Stemolecule™ MAPK Signaling Pathway Modulator Set contains three cell permeable small molecules known to modulate the mitogen-activated protein kinase (MAPK) signaling cascade. Stemolecule™ PD0325901 inhibits mitogen-activated protein kinase kinase (MAPK/ERK kinase or MEK). Stemolecule™ PD173074 is an ATP-competitive inhibitor of the fibroblast growth factor (FGF) receptor, which is known to activate the MAPK/ERK cascade. Stemolecule™ SC1 (Pluripotin) acts through dual inhibition of extracellular signal-regulated kinase 1 (ERK1) and Ras GTPase-activating protein (Ras-GAP).
Stemolecules™ PD0325901, PD173074, and SC1(Pluripotin) modulate MAPK signaling.
For research use only. Not for use in diagnostic procedures. Not for resale.
Product Specifications
| Size |
3 compounds
|
| Lot Number |
1260
|
| Quantity / Size |
3 compounds
|
| Set Components |
1. Stemolecule™ PD0325901 (Cat. No. 04-0006), 2 mg, Lot# 1144
2. Stemolecule™ PD173074 (Cat. No. 04-0008), 2 mg, Lot# 1161
3. Stemolecule™ SC1 (Pluripotin) (Cat. No. 04-0011), 1 mg, Lot# 1051
|
| Storage |
Store at 4°C. Protect from light. Following reconstitution, store aliquots at -20°C.
|
| Stability |
Components are stable for 6 months from date of receipt when stored as directed.
|
| Quality control |
The purity of Stemgent’s Stemolecules™ was determined by HPLC analysis. The accurate mass and structure of Stemgent’s Stemolecules™ were determined by mass spectrometry and NMR, respectively. Cellular toxicity of Stemgent’s Stemolecules™ was tested on mouse embryonic stem cells.
|
| Recommended Usage |
Refer to individual Stemolecule™ specification sheets.
|
| Related Products |
|
| Notice to Purchaser |
Purchaser represents and warrants that it will use the Stemolecule™ MAPK Signaling Pathway Modulator Set purely for research purposes. Not for diagnostic use, not for resale, and not for use in humans or veterinary applications. Stemgent will not be held responsible for patent infringement or other violations that may occur with the use of our products.
|
Technical Documents
Specifications
MSDS
|
|
|
|
|
