Scientific Advisory Board

• Daniel Anderson, Ph.D.
• Alan Colman, Ph.D.
• Hongkui Deng, Ph.D.
• Sheng Ding, Ph.D.
• Rudolf Jaenisch, M.D.
• Jeffrey Karp, Ph.D.
• Robert Langer, Sc.D.
• Douglas A. Melton, Ph.D.
• Roy Ogle, Ph.D.
• Thomas Roberts, Ph.D.
• Lee Rubin, Ph.D.
• Bob Weinberg, Ph.D.
• Leonard Zon, M.D.

Roy Ogle, Ph.D.

Extracellular matrices, growth factor receptors, and tissue engineering

Professor of Medicine, University of Virginia

Dr. Ogle trained at the University of Virginia and NIH and is currently Professor of Medicine, Biomedical Engineering and Plastic Surgery at the University of Virginia School of Medicine.

He is the recipient of over 30 research grants, holds several stem cell patents, and has authored more than 100 articles and the medical best-selling text, Craniofacial Surgery: Science and Surgical Technique. He has served on many federal and state advisory committees and review panels and testified at the US Senate Hearings on the NIH budget and embryonic stem cell research. Ogle also has appeared frequently in the popular media to explain stem cell biology to general audiences.

His current research focuses on regenerative medicine--both basic and translational research in stem cell biology and tissue engineering. Recent studies of adipose stem cells (ASCs) and stem cells of the dura mater (DSCs), which were discovered in this lab, include determination of the developmental plasticity, immunophenotypes and self-renewal properties of the cells in vitro, and their origin, migration and engraftment in vivo.

He also is using induced pluripotent stem cells derived from skin fibroblasts to derive lineage-restricted precursors to treat skeletal defects and brain strokes. His group has also fabricated nanofibrous protein meshes that are biomimetics of basement membranes of the early embryo, and which serve as effective substitutes for cellular feeder layers for propagation of pluripotent stem cells in vitro. Additional areas of interest are bioethics and public policy related to stem cell research and establishment of public stem cell banking systems in Virginia and abroad. Dr. Ogle received his Ph.D. from the University of Virginia and did his postdoctoral training at the Laboratory of Developmental Biology, NIDCR, NIH.