Reprogramming the industry
Solutions from Stemgent
Since the pioneering work by Dr. Shinya Yamanaka describing the reprogramming of somatic cells to a pluripotent-like state, the induced pluripotent stem (iPS) cell has become an invaluable tool for strategies in regenerative medicine, disease modeling, drug discovery, and basic research in cell development.
From traditional reprogramming methods (lentivirus, adenovirus) to non-integrating, non-viral technologies (mRNA, proteins), Stemgent provides the quality, knowledge, and expertise you depend on.
Choosing a reprogramming system
Stemgent offers a broad portfolio of cellular reprogramming systems to choose from - learn which system may be right for you.
High efficiency, non-virus, simple protocol. Eliminates safety concerns and bio-containment issues associated with virus, adjustable stoichiometry.
Compare reprogramming systems
See which system is right for your research
Benefits of using the Stemgent mRNA Reprogramming System as compared to other reprogramming methods
mRNA provides efficiencies greater than 1% as compared to other methods, which yield reprogramming efficiencies varying from 0.00001-0.01%. mRNA reprogramming does not require multi-step passaging or screening for virus or genomic integration once new colonies are derived.
Experimental timeline comparison
Generate colonies in as early as 16 days with mRNA reprogramming
Experiment timeline comparison shows mRNA reprogramming exhibits emerging virus-free iPS cells in less than 2 weeks (as compared to other systems that require additional work to screen cells for the presence of viral remnants).
Total time to generate a characterized iPS cell line using virus-based systems can take up to 25 weeks, whereas the Stemgent mRNA Reprogramming System can take as little as 9 weeks to generate a fully characterized and banked iPS cell line.
Note: Timelines are provided as a guideline for experimental planning and actual timelines can vary based on the cell type and experimental conditions.