Stemolecule™ GDC-0941

Catalog Size Price Quantity
04-0047 5 mg $139.00
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GDC 0941

Product Overview

Stemolecule™ GDC-0941 (pictilisib) is a cell-permeable, selective small molecule that inhibits Class I phosphatidylinositide 3-kinase (PI3K)1. The PI3K/ Akt signaling pathway plays a central role in diverse cellular functions such as cell growth and proliferation, but is also deregulated in a number of conditions, including cancer. GDC-0941 is a potent inhibitor of the PI3/Akt pathway, making it a valuable molecule for both the study and treatment of PI3/Akt related cancers2,3.

Product Specifications


5 mg

Alternate Name


Chemical Formula


Molecular Weight

705.8 (513.6 · 192.2)

CAS Number



Greater than 95% by HPLC analysis


White powder


For a 10 mM concentrated stock solution of GDC-0941, reconstitute the compound by adding 973.5 μl of DMSO to the entire contents of the vial. If precipitate is observed, warm the solution to 37°C for 2 to 5 minutes. For cell culture, the media should be prewarmed prior to adding the reconstituted compound. Note: for most cells, the maximum tolerance to DMSO is less than 0.5%. This molecule is soluble in DMSO at 100 mM.

Storage and Stability

Store powder at 4°C protected from light. Following reconstitution, store aliquots at -20°C. Stock solutions are stable for 6 months when stored as directed.

Quality Control

The purity of GDC-0941 was determined by HPLC analysis. The accurate mass was determined by mass spectrometry. Cellular toxicity of GDC-0941 was tested on mouse embryonic stem cells.

Specification Sheets

Safety Data Sheets

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