Size

2 mg

Concentration

10 mM in DMSO

Alternate Name

N-​[(2R)-​2,​3-​dihydroxypropoxy]-​3,​4-​difluoro-​2-​[(2-​fluoro-​4-​iodophenyl)amino]-​benzamide

Chemical Formula

C₁₆H₁₄F₃IN₂O₄ 

Molecular Weight

482.19

CAS Number

391210-10-9

Purity

Greater than 97% by HPLC analysis

Formulation

10 mM solution of PD0325901 in DMSO (2 mg in 414.8 μl)

Handling

Before opening, briefly centrifuge the vial to ensure full recovery of sample. Aliquotting the stock solution is recommended to avoid repetitive freeze-thaw cycles. For cell culture, the media should be prewarmed prior to adding the reconstituted compound. Note: for most cells, the maximum tolerance to DMSO is less than 0.5%.

Storage and Stability

Store solution at -20°C protected from light. Stable for 6 months from date of receipt when stored as directed.

Quality Control

The purity of PD0325901 was determined by HPLC analysis. The accurate mass was determined by mass spectrometry. Cellular toxicity of PD0325901 was tested on mouse embryonic stem cells.