Stemolecule™ Y27632 Dihydrochloride Hydrate

Catalog Size Price Quantity
04-0012-H-10 10 mg $499.00
Add To Cart
Order Offline
T: 877.228.9783
F: 617.812.5900
Figure 1: Y27632 Dihydrochloride Hydrate Structure

Product Overview

Y27632 is a cell-permeable small molecule Rho-associated kinase (ROCK) inhibitor1. Y27632 has been found to prevent apoptosis as well as enhance the survival and cloning efficiency of dissociated human embryonic stem (ES) cells without affecting their self-renewal properties or pluripotency2. This molecule has also been shown to enhance survival during the transplantation of ES cell-derived neural precursors3. Y27632 in combination with Pifithrin-µ significantly improves cell recovery after cryopreservation4.

Also available: Stemolecule™ Y27632 (04-0012), Stemolecule™ Y27632 in Solution (04-0012-02)

Stemgent conveniently provides all the components comprising the 5i/L/A media supplment necessary to support naive pluripotent stem cell applications.

5i (inhibitors):

L: Stemfactor™ LIF, Human Recombinant (03-0016), and

A: Stemfactor™ Activin A, Human Recombinant (03-0001)

Product Specifications


10 mg

Alternate Name

(1R,4r)-4-((R)-1-aminoethyl)-N-(pyridine-4-yl)cyclohexanecarboxamide dihydrochloride hydrate

Chemical Formula


Molecular Weight


CAS Number



Greater than 98%


White to pale yellow crystalline powder


Reconstitute in DMSO to the desired concentration. For reconstitution instructions please reference product specifications sheet.

Storage and Stability

Store powder at -20 °C protected from light. Following reconstitution, store aliquots at -20 °C. Stock solutions are stable for 6 months when stored as directed.

Quality Control

The purity of Y27632 was determined by HPLC analysis.
Elemental analysis, NMR, mass spectrum: consistent with structure.
Cellular toxicity of Y27632 was tested on mouse embryonic stem cells.

Specification Sheets

Safety Data Sheets

Related Products

Customers Also Purchased

1 kit $2,000.00
kit $695.00
1 Kit $1,395.00

Stemgent Comments and Reviews (0)

No comments or reviews yet. Be the first to leave a review.

Add a Comment

You must log-in or register as a Stemgent member to submit a comment.

You are fully responsible for the content you post. We encourage collaboration and helpful reviews among scientists and will use this feature to conduct helpful reviews of our products. Content that includes profanity, personal attacks or antisocial behavior (such as "spamming" or "trolling"), or other inappropriate content or material will be removed. We reserve the right to block any user who violates our terms of use, including removing all content posted by that user.