Stemolecule™ Doxycycline hyclate

Catalog Size Price Quantity
04-0016 10 mg $51.00
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Product Overview

Stemolecule Doxycycline hyclate (dox) is a broad spectrum antibiotic derivative of tetracycline and an inhibitor of matrix metalloproteinases1. Tetracycline-controlled transcriptional activation is a method of inducible expression whereby transcription is reversibly turned on or off in the presence of tetracycline or one of its derivatives such as dox2. For this type of reprogramming method, dox-inducible lentiviral reagents are used to induce the expression of virally transduced genes and generate induced pluripotent stem (iPS) cells from somatic cells3-7.


Product Specifications

Size

10 mg

Alternate Name

(2Z,4S,5S,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione; ethanol; hydrochloride

Chemical Formula

C22H24N2O8 · HCl · ½(H2O) · ½(C2H6O)

Molecular Weight

512.94

 CAS Number

24390-14-5

Purity

Greater than 98% by TLC analysis 

Formulation

Yellow to yellow with a green cast powder

Solubility

For a 10 mM concentrated stock solution of Doxycycline hyclate, reconstitute the compound by adding 1.95 ml of water to the entire contents of the vial.   

Storage and Stability

Store powder at 4°C protected from light. Following reconstitution, store aliquots at -20°C. Stock solutions are stable for 6 months when stored as directed. 

Quality control

The purity of Doxycycline hyclate was determined by TLC analysis. The accurate mass was determined by mass spectrometry. Cellular toxicity of Doxycycline hyclate was tested on mouse embryonic stem cells.  

Related Products

  • Stemgent® Dox Inducible Reprogramming Lentivirus Set: Mouse OSKM (conc) (Cat.No.ST000014)
  • Stemgent® Dox Inducible Reprogramming Lentivirus Set: Mouse OKSM (Cat.No.ST000021)
  • Stemgent® Dox Inducible Reprogramming Lentivirus Set: Human OKSM (Cat.No.ST000036) 
  • Stemgent® Dox Inducible Reprogramming Lentivirus Set: Human OKSM (conc.) (Cat.No.ST000037)
  • Stemgent® Dox Inducible Reprogramming Polycistronic Lentivirus Set: Mouse 4F2A (Cat.No.ST000043)
  • Stemgent® Dox Inducible Reprogramming Polycistronic Lentivirus Set: Human 4F2A LoxP (Cat.No.ST000066) 

Specification Sheets

Safety Data Sheets



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