Small Molecules for Stem Cell Research

Stemgent® offers a unique collection of small molecules, Stemolecules™, that can be used to dissect and modulate key signaling pathways involved in the self-renewal and differentiation of pluripotent stem cells, cellular reprogramming for the generation of induced pluripotent stem (iPS) cells, and induction and maintenance of the naïve state.

Stemolecules are stringently tested for high purity (≥98%), structurally verified by NMR and mass spectrometry, and tested for cytotoxicity on stem cells.  View Product Sheet  Ish Icon Brochure
Many Stemolecules are used routinely at ReproCELL to enhance iPS cell generation and maintain pluripotent stem cell cultures.

Stemolecule And Stemfactor Collection For Naive State Ipscs

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Mouse embryonic stem (ES) cells were maintained with 100 nM SC1 for 5 passages, fixed, and examined by immunocytochemistry for SSEA-1, Oct4 (shown here), Nanog, and Sox2. Results were comparable to cells maintained with 1000 units/ml LIF.

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Stemolecule™ CHIR99021

6-((2-((4-(2,4-dichlorocyclohexyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)nicotinonitrile

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Products (51)
Brand Name Catalog Number Size Price Quantity
Stemolecule™ A769662
04-0052 10 mg $179.00
Stemolecule™ A83-01
04-0014 2 mg $119.00
04-0014-10 10 mg $399.00
Stemolecule™ ALK5 Inhibitor (RepSox)
04-0015 1 mg $104.00
Stemolecule™ All-Trans Retinoic Acid
04-0021 100 mg $63.00
Stemolecule™ AM580
04-0077 5 mg $79.00
Stemolecule™ BI-D1870
04-0051 10 mg $439.00
Stemolecule™ BIO
04-0003 2 mg $99.00
Stemolecule™ BIX01294
04-0002 5 mg $104.00
Stemolecule™ CD437
04-0078 5 mg $118.00
Stemolecule™ CHIR99021
04-0004 2 mg $203.00
04-0004-10 10 mg $799.00
Stemolecule™ CHIR99021 in Solution
04-0004-02 2 mg (10 mM) $239.00
Stemolecule™ Cyclopamine
04-0022 2 mg $119.00
Stemolecule™ DAPT
04-0041 5 mg $146.00
Stemolecule™ Dorsomorphin
04-0024 2 mg $114.00
Stemolecule™ Doxycycline hyclate
04-0016 10 mg $51.00
Stemolecule™ ec23
SRP002 5mg $67.83
SRP002-2 2 x 5mg $135.66
Stemolecule™ Forskolin
04-0025 10 mg $146.00
Stemolecule™ GDC-0941
04-0047 5 mg $139.00
Stemolecule™ GSK429286A
04-0049 2 mg $179.00
Stemolecule™ IDE-1
04-0026 2 mg $199.00